Palonosetron’s preferred status
June 30th 2014Chemotherapy-induced nausea and vomiting (CINV) is among the most feared adverse effects associated with cancer treatment.1 The likelihood of patients experiencing this entity depends on both patient-related and treatment-related factors. Not all chemotherapeutic products induce equivalent amounts of CINV resulting in the formation of groups contingent on the frequency of CINV in patients receiving a product without antiemetic prophylaxis
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ACIP recommends needle-free, nasal flu vaccine for kids
June 30th 2014The Centers for Disease Control & Prevention’s (CDC) Advisory Committee on Immunization Practices (ACIP) has recommended that when available, the needle-free, nasal flu vaccine (Live Attenuated Influenza Vaccine [LAIV]) should be used for healthy children aged 2 to 8 years, who have no contraindications or precautions.
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Support consumer access to specialty medications through value-based insurance design
June 30th 2014The driving force behind consumer cost-sharing provisions for specialty medications is the acquisition cost and not clinical value. This appears to be true for almost all public and private health plans, says a new report from researchers at the University of Michigan Center for Value-Based Insurance Design (V-BID Center) and the National Pharmaceutical Council (NPC).
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Michigan merger points to national trend
June 26th 2014ACA’s emphasis on accountable care organizations, patient-centered medical homes, readmission penalties and pricing pressures on hospitals makes it attractive for hospitals to work together to share services and increase the efficiencies
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Testosterone products: FDA requires beefed up labeling to include risk of VTE, including DVT, PE
June 23rd 2014FDA is requiring manufacturers of all approved testosterone products to include a warning in the drug labeling about the risk of blood clots in the veins, also known as venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE).
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SSRIs in pregnancy not linked to cardiac defects in babies
June 20th 2014In pregnancy, first trimester use of antidepressants does not substantively increase the risk of specific cardiac defects in babies, and should not be an important consideration in the treatment decision, according to a study published in the June 19 issue of the New England Journal of Medicine.
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Sanofi and Regeneron Pharmaceuticals presented positive results from a phase 3 trial of investigational drug sarilumab in rheumatoid arthritis (RA) patients who were inadequate responders to methotrexate (MTX) therapy at the European League Against Rheumatism Annual Congress (EULAR 2014) Congress in Paris, France.
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ADA: Studies point to safety, efficacy profile for new insulin glargine product
June 19th 2014LY2963016 insulin glargine has a similar safety and efficacy profile to currently marketed insulin glargine, according to data recently presented the American Diabetes Association (ADA) Scientific Sessions in San Francisco.
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In a 52-week study of obese adults with type 2 diabetes on high insulin doses with or without metformin, adding empagliflozin to multiple daily insulin injections significantly reduced blood glucose and body weight with lower insulin doses compared with placebo, according to data recently presented at the American Diabetes Association (ADA) Scientific Sessions in San Francisco.
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In a 2-year study, empagliflozin as add-on to metformin demonstrated significantly greater decreases in hemoglobin A1c (a measure of average blood glucose over the past 2 to 3 months), body weight and blood pressure compared with glimepiride as add-on to metformin in adults with type 2 diabetes.
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ASCO: Ipilimumab improves recurrence-free survival in melanoma
June 17th 2014Ipilimumab (Yervoy, Bristol-Myers Squibb) significantly improved recurrence-free survival in patients with stage 3 melanoma in the adjuvant setting, compared to placebo, according to data presented at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago.
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ADA: Canola oil can help control blood glucose in people with type 2 diabetes
June 17th 2014Unhydrogenated, unsaturated vegetable oils, such as canola oil, can have health advantages when included in as part of a low-glycemic index (GI) diet in people with type 2 diabetes, according to research presented at American Diabetes Association Scientific Sessions in San Francisco, and published in Diabetes Care.
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