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Study Indicates Lorbrena not Cost-effective in Untreated NSCLC
Study Indicates Lorbrena not Cost-effective in Untreated NSCLC
Study Indicates Lorbrena not Cost-effective in Untreated NSCLC
June 18, 2021
Although Lorbrena can improve health outcomes, it is not as cost-effective an option compared with Xalkori.
Novel Immunotherapy Receives Breakthrough Designation in Advanced Melanoma
Novel Immunotherapy Receives Breakthrough Designation in Advanced Melanoma
Novel Immunotherapy Receives Breakthrough Designation in Advanced Melanoma
June 18, 2021
The therapy is a modified poliovirus vaccine that not only kills cancer cells but also can trigger long-term immune memory.
Biosimilars Pathway Survives With ACA Ruling
Biosimilars Pathway Survives With ACA Ruling
Biosimilars Pathway Survives With ACA Ruling
June 17, 2021
The Supreme Court’s dismissal of the latest challenge means patients will have access to lower-cost therapies, an advocacy group says.
Non-opioid Pain Therapeutic Achieves More Than 100 Formulary Approvals
Non-opioid Pain Therapeutic Achieves More Than 100 Formulary Approvals
Non-opioid Pain Therapeutic Achieves More Than 100 Formulary Approvals
June 17, 2021
The COX-2 inhibitor Anjeso, a faster-acting injectable formulation of meloxicam, reduces opioid use after surgery.
Reducing Cardiac Toxicity During Cancer Treatment
Reducing Cardiac Toxicity During Cancer Treatment
Reducing Cardiac Toxicity During Cancer Treatment
June 16, 2021
Chances of left ventricular ejection fraction almost disappeared when patient took the ACE-inhibitor lisinopril during treatment with trastuzumab/anthracycline, according to research presented at ASCO.
ASCO Abstracts Focus on Adverse Events of Checkpoint Inhibitors
ASCO Abstracts Focus on Adverse Events of Checkpoint Inhibitors
ASCO Abstracts Focus on Adverse Events of Checkpoint Inhibitors
June 16, 2021
Immune-related AEs can occur one to two years after treatment, are more common in combination treatments, and can be difficult to manage.
Bouquets and Brickbats for FDA OK of Alzheimer's Drug Aduhelm
Bouquets and Brickbats for FDA OK of Alzheimer's Drug Aduhelm
Bouquets and Brickbats for FDA OK of Alzheimer's Drug Aduhelm
June 15, 2021
The Alzheimer's Association praises the approval but not the price tag. A Harvard Medical School professor who resigned from an FDA advisory committee says the OK "was probably the worst approval decision in recent U.S. history" in his resignation letter.
With New Indication, Nurtec ODT Is a Drug for Both Prevention and Treatment of Migraine
With New Indication, Nurtec ODT Is a Drug for Both Prevention and Treatment of Migraine
With New Indication, Nurtec ODT Is a Drug for Both Prevention and Treatment of Migraine
June 14, 2021
Nurtec ODT is the first oral CGRP antagonist approved for migraine prevention, says its maker, Biohaven.
New Dry Eye Therapy Gains Formulary Coverage
New Dry Eye Therapy Gains Formulary Coverage
New Dry Eye Therapy Gains Formulary Coverage
June 14, 2021
Three commercial plans now cover the corticosteroid Eysuvis.
FDA Greenlights Controversial Aducanumab, Biogen's Alzheimer’s Treatment
FDA Greenlights Controversial Aducanumab, Biogen's Alzheimer’s Treatment
FDA Greenlights Controversial Aducanumab, Biogen's Alzheimer’s Treatment
June 7, 2021
Today's approval goes against the advice of an outside advisory committee.
FDA clears first chronic weight loss drug in 7 years
FDA clears first chronic weight loss drug in 7 years
FDA clears first chronic weight loss drug in 7 years
June 7, 2021
Semaglutide injection is a weekly injection for chronic weight management in adults.
Healthcare costs, lack of communication are of major concern to healthcare leaders
Healthcare costs, lack of communication are of major concern to healthcare leaders
Healthcare costs, lack of communication are of major concern to healthcare leaders
June 1, 2021
Around 49% of the more than 300 healthcare providers, hospital/health system executives, payers, advocacy groups, and academics surveyed by Get the Medications Right™ (GTMRx) Institute said the cost of healthcare is the biggest issue they face.
Substance abuse increase could cost the U.S. billions
Substance abuse increase could cost the U.S. billions
Substance abuse increase could cost the U.S. billions
June 1, 2021
Prevalent cases of opioid use disorder could total around 1.9 million in 2021 and could cost the U.S. billions to treat, data and analytics firm GlobalData said.
FDA OKs first targeted therapy for lung cancer with certain type of EGFR mutations
FDA OKs first targeted therapy for lung cancer with certain type of EGFR mutations
FDA OKs first targeted therapy for lung cancer with certain type of EGFR mutations
May 25, 2021
About 2% to 3% of patients with nonsmall cell lung cancer have EGFR exon 20 insertion mutations targeted by newly approved Rybrevant.
FDA OKs first-of-its-kind treatment for paroxysmal nocturnal hemoglobinuria
FDA OKs first-of-its-kind treatment for paroxysmal nocturnal hemoglobinuria
FDA OKs first-of-its-kind treatment for paroxysmal nocturnal hemoglobinuria
May 18, 2021
OptumRx had identified pegcetacoplan as one of the top 5 drugs in the pipeline this year.
Sanofi and GSK’s COVID-19 vaccine may be available this year
Sanofi and GSK’s COVID-19 vaccine may be available this year
Sanofi and GSK’s COVID-19 vaccine may be available this year
May 18, 2021
Sanofi and GlaxoSmithKline’s joint COVID-19 vaccine candidate achieved 95% to 100% seroconversion in a Phase 2 study.
5 drugs in the pipeline that could have a major impact this year
5 drugs in the pipeline that could have a major impact this year
5 drugs in the pipeline that could have a major impact this year
May 11, 2021
The drugs in development include Biogen’s controversial treatment for Alzheimer’s disease and three new drugs for atopic dermatitis.
Teva launches its version of erythromycin and Absorica
Teva launches its version of erythromycin and Absorica
Teva launches its version of erythromycin and Absorica
May 11, 2021
Teva is making the first generic version of Absorica (isotretinoin), a drug for the treatment of severe acne.
Blockbuster Farxiga Gets New Chronic Kidney Disease Indication
Blockbuster Farxiga Gets New Chronic Kidney Disease Indication
Blockbuster Farxiga Gets New Chronic Kidney Disease Indication
May 4, 2021
The AstraZeneca drug is the first SGLT2 inhibitor approved for chronic kidney disease regardless of whether the patient has diabetes.
U.S. pharmaceutical spending to slow relative to global trend
U.S. pharmaceutical spending to slow relative to global trend
U.S. pharmaceutical spending to slow relative to global trend
May 3, 2021
Global drug spending — excluding COVID-19 vaccines — is expected to reach an estimated $1.6 trillion by 2025, a new report says.
COVID-19 pushes up prescription drug spending of healthcare systems
COVID-19 pushes up prescription drug spending of healthcare systems
COVID-19 pushes up prescription drug spending of healthcare systems
April 28, 2021
The pandemic is expected to have a significant effect on drug costs this year and into 2022, a new report says.
Axsome Therapeutics antidepressant drug could become blockbuster
Axsome Therapeutics antidepressant drug could become blockbuster
Axsome Therapeutics antidepressant drug could become blockbuster
April 27, 2021
The major depressive disorder (MDD) market is expected to soar to $7.87 billion by 2029.
BMS’s Opdivo earns indication for gastric cancer
BMS’s Opdivo earns indication for gastric cancer
BMS’s Opdivo earns indication for gastric cancer
April 21, 2021
Opdivo is the first FDA-approved immunotherapy for the first-line treatment of gastric cancer.
FDA rescinds EUA for solo use of Lilly's bamlanivimab
FDA rescinds EUA for solo use of Lilly's bamlanivimab
FDA rescinds EUA for solo use of Lilly's bamlanivimab
April 19, 2021
The combination monoclonal antibody treatment of bamlanivimab and etesevimab still OK.
Gilead’s breast cancer treatment snags expanded indication
Gilead’s breast cancer treatment snags expanded indication
Gilead’s breast cancer treatment snags expanded indication
April 14, 2021
The new approval expands the drug's indication to include treatment in adult patients with unresectable locally advanced or metastatic triple-negative breast cancer.
Prozac, antifungal drug inhibit SARS-CoV-2 in new study
Prozac, antifungal drug inhibit SARS-CoV-2 in new study
Prozac, antifungal drug inhibit SARS-CoV-2 in new study
April 13, 2021
Two common antidepressant and antifungal drugs were very effective at inhibiting SARS-CoV-2, the virus that causes COVID-19, according to a new study.
FDA clears Qelbree, first new ADHD drug for children in more than a decade
FDA clears Qelbree, first new ADHD drug for children in more than a decade
FDA clears Qelbree, first new ADHD drug for children in more than a decade
April 7, 2021
The novel nonstimulant medication from Supernus Pharmaceuticals can be sprinkled on food.
FDA okays first CAR-T cell therapy for a specific myeloma
FDA okays first CAR-T cell therapy for a specific myeloma
FDA okays first CAR-T cell therapy for a specific myeloma
March 30, 2021
Bristol Myers Squibb and bluebird bio’s Abecma is the first B-cell maturation antigen (BCMA)-directed CAR-T cell immunotherapy for relapsed or refractory multiple myeloma after 4 or more prior lines of therapy.
A conversation about real-world data with COTA's Viraj Narayanan
A conversation about real-world data with COTA's Viraj Narayanan
A conversation about real-world data with COTA's Viraj Narayanan
March 30, 2021
Precision medicine may mean smaller clinical trials. Collecting real-world data can help supply some of the same information as a control group.
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