Patricia Weiser, Pharm.D.

In the U.S., nearly 200,000 new cases of lung cancer were reported in 2020, with over 100,000 deaths. While the number of lung cancer deaths has generally decreased over the past 20 years, lung cancer remains the leading cause of cancer deaths in the US and is the third most common type of cancer.

Mutations in the FLT3 gene are common in AML, occurring in around 30% of cases, and tend to be associated with poorer outcomes.

A study found that the mRNA-1647 vaccine candidate developed by Moderna elicited strong immune responses. The mRNA vaccine is now in phase 3 clinical trials to determine its effectiveness in protecting against CMV.

Initial treatments for lung adenocarcinomas may be effective at first, but sometimes these tumors can respond by turning into small cell lung cancer (SCLC), a more aggressive and difficult-to-treat disease.

Imbruvica is an oral medication prescribed to treat certain B-cell malignancies, including chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) and Waldenstrom macroglobulinemia.

The development of new and improved therapeutic agents has improved the treatment outcomes for MM over the past few decades. It remains unclear whether these racial disparities have persisted in the era of novel agents.

It is well-known that smoking is linked to a higher risk of cancer, and those who smoke can lower their risk by quitting. However, it remains unclear exactly how many years of continued smoking cessation are needed to see a substantial risk reduction.

A study published in The Lancet revealed the efficacy of a single-dose typhoid conjugate vaccine. The four-year, phase 3 trial assessed the vaccine's effectiveness in preventing typhoid fever in Malawian children.

The FDA orders new warnings for CAR-T cell therapies due to reports of T-cell malignancies, including fatal cases, applying to BCMA- and CD19-directed genetically modified autologous T-cell immunotherapies.

The FDA orders new warnings for CAR-T cell therapies due to reports of T-cell malignancies, including fatal cases, applying to BCMA- and CD19-directed genetically modified autologous T-cell immunotherapies.

Invivyd‘s request for EUA is supported by positive initial results from the CANOPY Phase 3 clinical trial of VYD222.

To date, two shingles vaccines have been marketed in the United States: Zostavax, approved in 2006, and Shingrix, approved in 2017. However, Zostavax is no longer available for treatment.

While tissue biopsy is currently recommended as the gold standard for determining mutations in non-small cell lung cancer, its success is not guaranteed, prompting the consideration of the liquid biopsy method as a viable alternative.

COVID-19 vaccines are currently administered intramuscularly. Studies indicate that intramuscular vaccine administration may not effectively generate antibodies and T cells against SARS-CoV-2 in the respiratory tract mucosa.

Trial results revealed that tumors shrank in 40% of patients who received the 10-mg dose of tarlatamab and in about 32% of those who received the 100-mg dose.

This study examined data from 589,722 individuals and found that those who were vaccinated had a lower incidence of long COVID compared to those who were unvaccinated.

Vtama is a steroid-free cream that works by targeting the aryl hydrocarbon receptor, which plays a role in regulating immune responses.

Despite its efficacy, PrEP remains underutilized compared to the need for it. High costs are among the barriers to PrEP use, along with limited knowledge among clinicians, lack of health insurance, stigma, and underestimation of personal HIV risk.

People with moderate or severe hemophilia had worse joint status, lower pain thresholds, and poorer quality of life compared with people with mild hemophilia or healthy controls.

Pfizer and BioNTech released positive top-line data for their mRNA-based combination vaccine that targets influenza and COVID-19.