Ingenol mebutate gel is effective treatment for actinic keratosis, study shows
March 23rd 2012Ingenol mebutate topical gel (0.015% for face and scalp and 0.05% for trunk and extremities) was effective for treating actinic keratoses, a common precursor to sun-related, squamous cell carcinoma, according to a new study.
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Alzheimer’s drugs donepezil, memantine show some benefits in study
March 23rd 2012A new study of patients with moderate-to-severe Alzheimer's disease found that extended treatment with donepezil could improve cognition and function for even severe patients; however, experts caution that the benefits of the drug were modest.
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Clinical pharmacists can help reduce discrepancies in patient medication histories
March 23rd 2012Clinical pharmacists were instrumental in reducing errors in patients' physician-acquired medication histories, according to a study published online on March 13 in the Annals of Pharmacotherapy.
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Study highlights need to treat female nursing-home patients for vitamin D deficiency
March 23rd 2012The majority of older women in nursing homes are likely to be deficient in vitamin D during winter months, and those with the lowest levels are at a significantly increased risk of death, according to a study published online February 8, in the Journal of Clinical Endocrinology.
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AMCP pleased FDA exploring benefits of expanding availability of OTC drugs
March 22nd 2012The Academy of Managed Care Pharmacy (AMCP) is pleased that FDA is exploring the public health benefit of approving certain drugs that would otherwise require a prescription for nonprescription use under conditions of safe use, an AMCP official said in written testimony Thursday.
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Study shows CNS drugs take longer than others to develop, receive approval
March 16th 2012The time from investigational new drug application filing to NDA/BLA approval by FDA of drugs for central nervous system disorders and the subsequent regulatory approval can take 35% longer than other therapeutic categories, according to a recent analysis published in the March/April Tufts Center for the Study of Drug Development Impact Report.
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Study: Adding prednisone to rheumatoid arthritis treatment improves symptoms
March 16th 2012Patients' rheumatoid arthritis symptoms improved after adding prednisone at the start of a methotrexate-based treatment strategy, according to research published in the March 6 issue of the Annals of Internal Medicine.
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Soldiers with PTSD, other mental health issues, more likely to get high-risk opioids
March 16th 2012Veterans of Afghanistan and Iraq with mental health issues, especially post-traumatic stress disorder (PTSD), were more likely to receive high-risk opioids for pain, and those with PTSD were more likely to suffer adverse clinical outcomes, according to a new study.
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MALD model helps predict death versus recovery for APAP overdose
March 16th 2012A mathematical model that uses laboratory values commonly available on admission can help physicians estimate acetaminophen (APAP: N-acetyl-para-aminophenol) overdose amount, time elapsed since overdose, and potential outcome, according to a study published online February 13 in Hepatology.
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FDA approves first oral contraceptive to treat heavy menstrual bleeding
March 15th 2012FDA has approved a new indication for estradiol valerate and estradiol valerate/dienogest (Natazia, Bayer HealthCare Pharmaceuticals) tablets for the treatment of heavy menstrual bleeding (HMB) that is not caused by any diagnosed conditions of the uterus.
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FDA approves first generic Lexapro to treat depression, anxiety disorder
March 14th 2012Teva/IVAX Pharmaceuticals gained FDA approval for the first generic version of Lexapro (Forest) to treat both depression and generalized anxiety disorder in adults. The company will have 180 days to exclusively sell the product.
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FDA approves first cell-based product to treat oral mucogingival conditions in adults
March 9th 2012FDA approved the first cell-based product made from allogeneic human cells and bovine collagen (Gintuit, Organogenesis) for in the treatment of mucogingival conditions in adults, the agency announced Friday.
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Some antipsychotics more dangerous for elderly dementia patients
March 9th 2012Antipsychotic medication should be used on elderly dementia patients only in cases of clear need, authors of a recent study said, but they found that some antipsychotics are more dangerous than others after examining data from thousands of nursing-home residents aged 65 or older.
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Bevacizumab improves vision for patients with AMD
March 9th 2012A treat-and-extend regimen of intravitreal bevacizumab (Avastin, Genentech) produced "significant visual improvements" for eyes with neovascular age-related macular degeneration, according to an article published in the March issue of the American Journal of Ophthalmology.
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NAMS highlights benefit-risk ratio of hormone therapy for menopause
March 9th 2012The 2012 Hormone Therapy Position Statement of The North American Menopause Society (NAMS) updates the evidence-based position statement published by NAMS in 2010 regarding recommendations for hormone therapy for postmenopausal women.
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