Study: Similar safety, efficacy with dabigatran versus warfarin in diabetic patients with Afib
November 29th 2012Patients with nonvalvular atrial fibrillation (NVAF) who also have diabetes experienced similar safety and efficacy with dabigatran etexilate mesylate (Pradaxa) 150 mg or dabigatran 110 mg relative to warfarin, in comparison to patients without diabetes who have NVAF, according to data presented at American Heart Association's Scientific Sessions 2012.
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No big surprises in ACA insurance regulations
November 26th 2012The Obama administration moved ahead to implement provisions in the healthcare law that would make it illegal for insurance companies to deny coverage for those with pre-existing conditions. Other provisions of the Affordable Care Act (ACA) also would make it easier for consumers to compare health plans and easier for employers to promote and encourage employee wellness.
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Best tocolytic therapy options outlined for preterm delivery
November 21st 2012Prostaglandin inhibitors, such as celecoxib (Celebrex, Pfizer) and indomethacin (Indocin, Merck and Lundbeck) and calcium channel blockers, such as nifedipine and nicardipine (Cardene, Cornerstone Therapeutics) had the highest probability of delaying premature labor by 48 hours and improving maternal and neonatal outcomes, according to a systemic review and network meta-analysis published in a recent issue of BMJ.
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Medication use for normal aging conditions overtake costs of treating most chronic diseases
November 16th 2012Prescription-drug treatment regimens for conditions are a normal part of aging are now costing the nation more than many serious and potentially life-threatening disease, according to new research from Express Scripts.
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FDA Commissioner Margaret Hamburg was asked if the fungal meningitis outbreak could have been prevented by FDA during a 4-hour hearing Nov. 14 headed by the chairman of the House Energy and Commerce oversight subcommittee. Her answer was that FDA had limited authority because the New England Compounding Center (NECC), Framingham, Mass., was a ?compounding pharmacy,? which is regulated by the state Board of Pharmacy.
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Sanofi lowers price of Zaltrap after Sloan-Kettering refusal to use it
November 15th 2012Sanofi is lowering the price of ziv-aflibercept (Zaltrap) for previously treated colorectal cancer by half after physicians at Memorial Sloan Kettering Cancer Center (MSKCC) said that they would not use the drug, according to The New York Times.
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Updated antiplatelet guideline highlights surgical bleeding risk
November 9th 2012The Society of Thoracic Surgeons has updated its clinical practice guidelines on use of antiplatelet drugs during heart surgery. The new guideline, published in the November 2012 issue of The Annals of Thoracic Surgery, takes into account newly available antiplatelet therapies, new scientific information, and a broader use of antiplatelet drugs such as before lung and vascular procedures, according to Newswise.
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FDA fast tracks drug for metastatic breast cancer
November 9th 2012FDA has fast-tracked etirinotecan pegol (NKTR-102) (Nektar Therapeutics) for the treatment of patients with locally recurrent or metastatic breast cancer progressing after treatment with an anthracycline, a taxane, and capecitabine (ATC).
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Mass. Board of Pharmacy director fired for not investigating complaint about NECC
November 8th 2012James D. Coffey, RPh, director of the Massachusetts Board of Registration in Pharmacy, has been removed from his position after allegedly failing to follow up on a complaint about the New England Compounding Pharmacy (NECC) from the Colorado Board of Pharmacy in July. In addition, Susan Manning, the Massachusett’s Board attorney has been placed on administrative leave, according to a statement from the Massachusetts Department of Public Health.
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Details illuminate start of fungal meningitis outbreak
November 8th 2012Investigators from the Tennessee Department of Health and the Centers for Disease Control and Prevention (CDC) provided an aggressive public health response following a single case of Aspergillus fumigatus meningitis in an immunocompetent adult who had received an epidural injection of preservative-free methylprednisolone acetate at a clinic in Tennessee, according to a report published Nov. 7 in the New England Journal of Medicine.
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