CDC: Flu vaccine reduced kid’s risk of ICU flu admission by three-fourths
March 31st 2014Influenza vaccination reduced children’s risk of pediatric intensive care unit (PICU) admission for flu by three-fourths during 2010 to 2011 and 2011to 2012, according to a Centers for Disease Control and Prevention (CDC) study published online March 26 in the Journal of Infectious Diseases.
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ACC: New findings presented on dabigatran antidote
March 31st 2014Idarucizumab (Fab, Boehringer Ingelheim), an investigational humanized antibody fragment being studied as a specific antidote for dabigatran (Pradaxa), reversed dabigatran anticoagulation, even in the presence of elevated dabigatran levels and life-threatening bleeding from severe trauma, in animals, according to a study presented at the American College of Cardiology 63rd Annual Scientific Session (ACC.14), Washington, D.C.
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ACC: Investigational PCSK9 inhibitor alirocumab shows promise in phase 3 monotherapy study
March 31st 2014Data from a phase 3 study comparing the low-density lipoprotein-cholesterol (LDLc)–lowering efficacy and safety of alirocumab, an investigational PCSK9 inhibitor, versus ezetemibe in patients not receiving statin or other lipid-lowering therapies was presented at the ACC.14, the American College of Cardiology’s 63rd Annual Scientific Session & Expo in Washington, D.C.
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FDA has approved Coagulation Factor IX (Recombinant), Fc Fusion Protein (Alprolix, Biogen Idec), for use in adults and children who have hemophilia B; it also granted the product orphan-drug designation. Alprolix is the first hemophilia B treatment designed for less frequent injections when used to prevent or reduce bleeding frequency.
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6 key tips to help alleviate drug shortages
March 28th 2014The American Society of Health-System Pharmacists (ASHP), the Institute for Safe Medication Practices (ISMP), the American Hospital Association (AHA), and other healthcare groups have developed a number of long-term strategies to address drug shortages and released their recommendations in a report, ASHP announced last week.
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Xartemis XR receives FDA approval: May reduce opioid abuse
March 28th 2014Oxycodone hydrochloride and acetaminophen (Xartemis XR, Mallinckrodt) Extended-Release Tablets (CII) were approved for the management of acute pain requiring opioid treatment. Xartemis XR has been specifically formulated to reduce abuse, according to the drug’s manufacturer.
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Serious side effects may be caused by OTC cold meds
March 26th 2014Over-the-counter (OTC) sinus and pain drugs combining phenylephrine and acetaminophen-including Tylenol Sinus, Sudafed PE Sinus, Benadryl Allergy Plus Sinus, and Excedrin Sinus Headache-might cause serious side effects such as high blood pressure, dizziness, and tremors, according to a new study published in the New England Journal of Medicine.
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Financial hardship linked to medication underuse in chronically ill
March 26th 2014Chronically ill adults don’t have consistent access to food due to lack of financial stability were significantly more likely to report cost-related medication underuse, according to a new study published in The American Journal of Medicine. Cost-related medication underuse refers to taking less medication than prescribed, or not taking it at all because of financial concerns.
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Specialty drug pricing pushing envelope for hospital pharmacies
March 26th 2014Specialty drug pricing and generic drug pricing, especially around single-source generics during their exclusivity period, should be on the radar screens of hospital and managed care decision-makers, according to Catamaran’s 2013 Drug Trend data, which represents 25 million consumers.
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Skin abscesses with MRSA: How to manage
March 26th 2014It has been more than a decade since the clinical battle began with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), and physicians are still trying to figure out how to diagnose, treat, and prevent this virulent form of staph infection, which is immune to many antibiotics.
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