GLP-1s Are an 'Adjunct to Lifestyle Management' | ACC 2025

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In this second part of his interview with Managed Healthcare Executive, John B. Buse, M.D., Ph.D., a professor at the University of North Carolina (UNC) School of Medicine and director of the UNC's Diabetes Care Center, discusses lifestyle management and GLP-1s.

In this second part of his interview with Managed Healthcare Executive, John B. Buse, M.D., Ph.D., a professor at the University of North Carolina (UNC) School of Medicine and director of the UNC's Diabetes Care Center, discusses lifestyle management and GLP-1s.

He noted that the GLP-1 trials included lifestyle management: "It is not instead of lifestyle management," he said, referring to taking GLP-1s. "It is really an adjunct to lifestyle management."

He quickly added that for some people it is an absolutely essential adjunct. Buse said that in the United States, with people being busy and sometimes holding two jobs, eating a healthy diet consistently and getting physical activity regularly is "very, very hard to do."

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