Serious side effects may be caused by OTC cold meds
March 26th 2014Over-the-counter (OTC) sinus and pain drugs combining phenylephrine and acetaminophen-including Tylenol Sinus, Sudafed PE Sinus, Benadryl Allergy Plus Sinus, and Excedrin Sinus Headache-might cause serious side effects such as high blood pressure, dizziness, and tremors, according to a new study published in the New England Journal of Medicine.
Read More
Financial hardship linked to medication underuse in chronically ill
March 26th 2014Chronically ill adults don’t have consistent access to food due to lack of financial stability were significantly more likely to report cost-related medication underuse, according to a new study published in The American Journal of Medicine. Cost-related medication underuse refers to taking less medication than prescribed, or not taking it at all because of financial concerns.
Read More
Specialty drug pricing pushing envelope for hospital pharmacies
March 26th 2014Specialty drug pricing and generic drug pricing, especially around single-source generics during their exclusivity period, should be on the radar screens of hospital and managed care decision-makers, according to Catamaran’s 2013 Drug Trend data, which represents 25 million consumers.
Read More
Skin abscesses with MRSA: How to manage
March 26th 2014It has been more than a decade since the clinical battle began with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), and physicians are still trying to figure out how to diagnose, treat, and prevent this virulent form of staph infection, which is immune to many antibiotics.
Read More
Antibiotic-resistant bacteria on rise among US children
March 24th 2014Infections caused by a specific type of antibiotic-resistant bacteria are on the rise in US children, according to study published in the Journal of the Pediatric Infectious Diseases Society. While still rare, the bacteria are increasingly found in children of all ages, especially those aged 1 to 5 years old, raising concerns about dwindling treatment options.
Read More
Study supports long-acting bupivacaine for postsurgical pain after joint replacement
March 24th 2014Local infiltration with long-acting liposome bupivacaine (Exparel) as part of a non-narcotic multimodal pain management regimen for joint replacement surgeries, meaningfully improves patient and hospital economic outcomes, according to new data presented at the 81st annual meeting of the American Academy of Orthopaedic Surgeons (AAOS).
Read More
Vaccine administration errors: How to avoid
March 24th 2014Influenza, zoster, hepatitis A, hepatitis B, and the diphtheria and tetanus toxoids and acellular pertussis adsorbed (DTaP) are among the most common vaccines involved in medication errors in the United States, according to a new report from the Institute for Safe Medication Practices (ISMP). The other most common problematic vaccines include Haemophilus influenzae type b conjugate, Tdap, DTaP-IPV, human papillomavirus (HPV4), and measles, mumps, rubella, and varicella (MMRV).
Read More
Apixaban now approved to reduce risk of blood clots after hip, knee surgery
March 22nd 2014FDA has approved apixaban (Eliquis, Bristol-Myers Squibb and Pfizer) for the prophylaxis of deep vein thrombosis (DVT), which may lead to pulmonary embolism (PE), in patients who have undergone hip- or knee-replacement surgery.
Read More
Most C difficile in kids linked to antibiotics
March 21st 2014The majority of all pediatric Clostridium difficile infections are the result of a recent course of antibiotics prescribed by a physician for some other condition, according to a new study by the Centers for Disease Control and Prevention (CDC).
Read More
Once-daily topiramate XR approved for refractory seizures
March 18th 2014FDA approved once-daily topiramate (Qudexy XR, Upsher-Smith Laboratories) extended-release capsules for initial monotherapy in patients aged 10 years and older with partial-onset seizures (POS) or primary generalized tonic-clonic seizures.
Read More
VTE complications reduced with perioperative statin therapy
March 18th 2014When used in conjunction with conventional blood clot prevention therapies, statins significantly reduced the risk for venous thromboembolic (VTE) events following total joint replacement (TJR) surgery, according to research presented recently at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS).
Read More
Dabigatran bleeding risk: ISMP calls for FDA action
March 16th 2014The high risk of bleeding in patients taking the anticoagulant dabigatran (Pradaxa) has been a major problem that the manufacturer and health experts have been trying to find solutions for over the last four years. Sixteen percent of patients experienced a bleed in one year, including 3.3% who had bleeds that required emergency medical treatment, according to one clinical trial.
Read More
Penicillin ‘allergy’ label at hospital admission can lead to longer hospital stays
March 12th 2014A penicillin "allergy" label adversely affects the quantity and quality of healthcare in hospitalized patients, according to a study in the March issue of the Journal of Allergy and Clinical Immunology. The penicillin allergy label is the most common drug "allergy" listed in medical records during hospital admissions.
Read More