Fixed-dose combination shows improved lung function in COPD patients: Study
May 22nd 2014The fixed-dose combination of tiotropium and olodaterol (T+O FDC) has the potential to become a viable once-daily chronic obstructive pulmonary disease (COPD) treatment, according to data presented at the 2014 American Thoracic Society (ATS) International Conference, in San Diego.
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Clinicians should not start or continue statins in patients with sepsis-associated acute respiratory distress syndrome (ARDS), according to a study published in the May 18, 2014, New England Journal of Medicine, along with accompanying editorials evaluating the research’s goals and outcomes.
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Investigational TKI nintedanib slowed lung function loss in idiopathic pulmonary fibrosis
May 21st 2014Nintedanib, an investigational small molecule tyrosine kinase inhibitor (TKI), slowed lung function loss in patients with idiopathic pulmonary fibrosis (IPF), according to the results of 2 pivotal phase 3 trials presented at the American Thoracic Society International Conference in San Diego.
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Precision system "prints" individualized med dosages for patients
May 19th 2014A mathematical model to predict-and a portable inkjet technology to produce-exact medication dosages tailored for specific patients, an advance in personalized medicine that could improve drug effectiveness and reduce adverse reactions, has been created by Purdue University researchers.
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Shortage of IV metronidazole antibiotic prompts indication-specific alternatives
May 16th 2014There has been a recent national backorder of iv Metronidazole (Flagyl) due to manufacturing delays with Hospira. As a result of this delay Hospira has not been able to provide a tentative timeline or estimate date of when IV metronidazole will be available to purchasers/buyers once again. While this situation plays out, there are general management strategies that might be implemented based on the facility.
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CDC releases guidelines for HIV preventive meds
May 16th 2014The Centers for Disease Control and Prevention (CDC) released a new set of comprehensive guidelines that recommends that physicians should consider prescribing antiretroviral medication to individuals who are not infected with HIV but are at high risk of infection.
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Meds for alcohol use disorders effective, but underutilized
May 15th 2014Several medications can help people with alcohol use disorders to maintain abstinence or to reduce drinking, when added to psychosocial interventions. Two drugs, acamprosate and oral naltrexone, have the best evidence supporting their benefits, according to an analysis of more than 100 studies examining the use of medications to treat these conditions.
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Drugs in Perspective: Sovaldi (sofosbuvir)
May 15th 2014Hepatitis C is a viral disease that causes the inflammation of the liver which can ultimately lead to a diminished liver function or liver failure. The majority of individuals who are infected with HCV do not present with any symptoms of the disease until the appearance of liver damage. According to the Centers for Disease Control and Prevention it is estimated that approximately 3.2 million American are infected with hepatitis C and globally about 150 million people have hepatitis C. Up to 85% of those who are initially infected with HCV will not eliminate the virus and become chronically infected.
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Eliminating med copays after heart attack can improve outcomes for non-white patients
May 14th 2014Eliminating copays for preventive medications prescribed for post-heart attack patients can significantly improve medication adherence for all patients, according to a study published in Health Affairs.
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Rx errors in HIV patients can be reduced by pharmacists
May 14th 2014A pharmacist who is proficient at monitoring and ensuring appropriate therapy, as well as providing necessary medication counseling, will greatly enhance compliance and reduce potential adverse drug reactions and interactions in HIV-positive hospital patients, according to FormularyWatch advisor James M. Wooten, PharmD, associate professor, department of medicine, section of clinical pharmacology, University of Missouri-Kansas City.
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Drug combo reduces UTIs in kids by up to 80%
May 12th 2014Long-term use of a combination antimicrobial trimethoprim–sulfamethoxazole (TMP/SMZ) reduces the risk of recurrent urinary tract infection (UTI) by up to 80% in children with the urinary condition vesicoureteral reflux compared to placebo, according to a study published online May 4 in the New England Journal of Medicine.
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FDA approves clot-busting vorapaxar
May 9th 2014FDA approved vorapaxar (Zontivity, Merck Sharp & Dohme Corp., a subsidiary of Merck) tablets to reduce the risk of heart attack, stroke, cardiovascular death, and need for procedures to restore the blood flow to the heart in patients with a previous heart attack or blockages in the arteries to the legs.
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