Noninvasive Blood-based Model Developed to Assess Extent and Severity of Ulcerative Colitis
December 18th 2023In an effort to reduce financial and other quality of life burdens for individuals living with ulcerative colitis, Hongliang Chen and his colleagues from the Department of Gastroenterology and Hepatology at four medical centers in northeast China sought to develop a routine blood-based tool for assessing the extent and severity of ulcerative colitis.
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Fertility Treatments Found to Be Equally Effective in Females with PCOS as in Those Without
December 18th 2023In a study recently published in the journal Fertility and Sterility, researchers from the University of Queensland in Brisbane, Australia, evaluated the fertility treatment pathways used by participants with and without PCOS to determine which pathways resulted in more live births.
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Air Pollution May Negatively Affect Male Reproductive Health
November 30th 2023A potential mechanism by which air pollutants may affect reproductive health is by endocrine disruption. Air pollutants are made up of mixtures of particulate matter that may include endocrine disruptors, such as polycyclic aromatic hydrocarbons (PAHs) and heavy metals.
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Study Finds Higher B-Cell Levels in African American Patients with Multiple Sclerosis
November 8th 2023It is believed that reasons for these racial disparities may include socioeconomic factors, but the true causes are not fully understood. Some researchers believe that immunologic differences may also play a role.
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PML, a Rare Side Effect of Tysabri, Found to Worsen Long-Term Disability in Patients with MS
October 11th 2023Progressive multifocal leukoencephalopathy (PML) is caused by John Cunningham virus (JCV). A recently published study suggests that the number of cases of PML related to Tysabri (natalizumab) have been decreasing perhaps as a result of increased monitoring.
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The similarity of symptoms means children already diagnosed with atopic dermatitis may not receive patch testing for allergic contact dermatitis, resulting in underdiagnosis of the comorbidity, say the authors of a study published in the Journal of the American Academy of Dermatology.
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Research has shown that patients with inflammatory bowel disease, including ulcerative colitis, treated with TNF-alpha blockers have a lower antibody response and a shorter duration of immunity than those who receive integrin receptor antagonists, such as Entyvio (vedolizumab), or no medication at all.
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Statin Use May Lower Risk of Colorectal Cancer in Patients with Ulcerative Colitis
September 8th 2023In an observational cohort study published in the September 2023 issue of The Lancet, Jiangwei Sun, Ph.D., from the Karolinska Institutet in Stockholm, Sweden, and his colleagues compared statin users with non-statin users to determine the risk of colorectal cancer in patients with IBD.
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